BDBM131006 US8829000, 6

SMILES: CC(C)c1ncc2n1c1ccc(Cl)cc1[nH]c2=O

InChI Key: InChIKey=VJVYCJIULNTODR-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 131006   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cGMP-specific 3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM131006 (US8829000, 6) Show SMILES CC(C)c1ncc2n1c1ccc(Cl)cc1[nH]c2=O Show InChI InChI=1S/C13H12ClN3O/c1-7(2)12-15-6-11-13(18)16-9-5-8(14)3-4-10(9)17(11)12/h3-7H,1-2H3,(H,16,18)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.26E+3	n/a	n/a	n/a	n/a	n/a	30
ASKA Pharmaceutical Co., Ltd. US Patent					Assay Description By a method similar to the measurement of PDE9-inhibiting activity, PDE5-inhibiting activity of each of the test compounds was measured, percent inhi...				US Patent US8829000 (2014) BindingDB Entry DOI: 10.7270/Q2K072ZX
					More data for this Ligand-Target Pair
Phosphodiesterase 9A (Homo sapiens (Human))	BDBM131006 (US8829000, 6) Show SMILES CC(C)c1ncc2n1c1ccc(Cl)cc1[nH]c2=O Show InChI InChI=1S/C13H12ClN3O/c1-7(2)12-15-6-11-13(18)16-9-5-8(14)3-4-10(9)17(11)12/h3-7H,1-2H3,(H,16,18)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	30
ASKA Pharmaceutical Co., Ltd. US Patent					Assay Description To 150 uL of buffer B (70 mmol/L Tris-HCl, pH7.5, 16.7 mmol/L MgCl2, 33.3 nmol/L [3H]-cGMP) solution containing [3H]-cGMP (specific activity=244.2 GB...				US Patent US8829000 (2014) BindingDB Entry DOI: 10.7270/Q2K072ZX
					More data for this Ligand-Target Pair