null

SMILES: OC(=O)CCc1ncc2n1c1ccc(Br)cc1[nH]c2=O

InChI Key: InChIKey=ZEDCCDVXWIERFN-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 131012   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cGMP-specific 3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM131012 (US8829000, 180) Show SMILES OC(=O)CCc1ncc2n1c1ccc(Br)cc1[nH]c2=O Show InChI InChI=1S/C13H10BrN3O3/c14-7-1-2-9-8(5-7)16-13(20)10-6-15-11(17(9)10)3-4-12(18)19/h1-2,5-6H,3-4H2,(H,16,20)(H,18,19)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.81E+3	n/a	n/a	n/a	n/a	n/a	30
ASKA Pharmaceutical Co., Ltd. US Patent					Assay Description By a method similar to the measurement of PDE9-inhibiting activity, PDE5-inhibiting activity of each of the test compounds was measured, percent inhi...				US Patent US8829000 (2014) BindingDB Entry DOI: 10.7270/Q2K072ZX
					More data for this Ligand-Target Pair
High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A (Homo sapiens (Human))	BDBM131012 (US8829000, 180) Show SMILES OC(=O)CCc1ncc2n1c1ccc(Br)cc1[nH]c2=O Show InChI InChI=1S/C13H10BrN3O3/c14-7-1-2-9-8(5-7)16-13(20)10-6-15-11(17(9)10)3-4-12(18)19/h1-2,5-6H,3-4H2,(H,16,20)(H,18,19)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	30
ASKA Pharmaceutical Co., Ltd. US Patent					Assay Description To 150 uL of buffer B (70 mmol/L Tris-HCl, pH7.5, 16.7 mmol/L MgCl2, 33.3 nmol/L [3H]-cGMP) solution containing [3H]-cGMP (specific activity=244.2 GB...				US Patent US8829000 (2014) BindingDB Entry DOI: 10.7270/Q2K072ZX
					More data for this Ligand-Target Pair