BDBM13109 CGS 27023A Analog 37::N-hydroxy-2-[(4-methoxybenzene)[2-(morpholin-4-yl)ethyl]sulfonamido]acetamide

SMILES: COc1ccc(cc1)S(=O)(=O)N(CCN1CCOCC1)CC(=O)NO

InChI Key: InChIKey=JKXLPZUCXZNXTD-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 13109   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Stromelysin-1 (Homo sapiens (Human))	BDBM13109 (CGS 27023A Analog 37 | N-hydroxy-2-[(4-methoxybenz...) Show SMILES COc1ccc(cc1)S(=O)(=O)N(CCN1CCOCC1)CC(=O)NO Show InChI InChI=1S/C15H23N3O6S/c1-23-13-2-4-14(5-3-13)25(21,22)18(12-15(19)16-20)7-6-17-8-10-24-11-9-17/h2-5,20H,6-12H2,1H3,(H,16,19)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	236	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Pharmaceuticals					Assay Description Stromelysin inhibitory activity is based on the hydrolysis of substance P by recombinant human stromelysin to generate a fragment, substance P 7-11, ...				J Med Chem 40: 2525-32 (1997) Article DOI: 10.1021/jm960871c BindingDB Entry DOI: 10.7270/Q2MW2FC7
					More data for this Ligand-Target Pair