BDBM13129 CGS 27023A Analog 61::benzyl N-[(5R)-5-[benzyl(4-methoxybenzene)sulfonamido]-5-(hydroxycarbamoyl)pentyl]carbamate

SMILES: COc1ccc(cc1)S(=O)(=O)N(Cc1ccccc1)[C@H](CCCCNC(=O)OCc1ccccc1)C(=O)NO

InChI Key: InChIKey=KTTAUIWWFGTEIT-AREMUKBSSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 13129   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Stromelysin-1 (Homo sapiens (Human))	BDBM13129 (CGS 27023A Analog 61 | benzyl N-[(5R)-5-[benzyl(4-...) Show SMILES COc1ccc(cc1)S(=O)(=O)N(Cc1ccccc1)[C@H](CCCCNC(=O)OCc1ccccc1)C(=O)NO |r| Show InChI InChI=1S/C28H33N3O7S/c1-37-24-15-17-25(18-16-24)39(35,36)31(20-22-10-4-2-5-11-22)26(27(32)30-34)14-8-9-19-29-28(33)38-21-23-12-6-3-7-13-23/h2-7,10-13,15-18,26,34H,8-9,14,19-21H2,1H3,(H,29,33)(H,30,32)/t26-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Pharmaceuticals					Assay Description Stromelysin inhibitory activity is based on the hydrolysis of substance P by recombinant human stromelysin to generate a fragment, substance P 7-11, ...				J Med Chem 40: 2525-32 (1997) Article DOI: 10.1021/jm960871c BindingDB Entry DOI: 10.7270/Q2MW2FC7
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