BDBM13132 2-[benzyl(4-methoxybenzene)sulfonamido]-N-hydroxy-3-(4-hydroxyphenyl)propanamide::CGS 27023A Analog 64

SMILES: COc1ccc(cc1)S(=O)(=O)N(Cc1ccccc1)C(Cc1ccc(O)cc1)C(=O)NO

InChI Key: InChIKey=AZLPLQRRFWWDQE-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 13132   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Stromelysin-1 (Homo sapiens (Human))	BDBM13132 (2-[benzyl(4-methoxybenzene)sulfonamido]-N-hydroxy-...) Show SMILES COc1ccc(cc1)S(=O)(=O)N(Cc1ccccc1)C(Cc1ccc(O)cc1)C(=O)NO Show InChI InChI=1S/C23H24N2O6S/c1-31-20-11-13-21(14-12-20)32(29,30)25(16-18-5-3-2-4-6-18)22(23(27)24-28)15-17-7-9-19(26)10-8-17/h2-14,22,26,28H,15-16H2,1H3,(H,24,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	65	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Pharmaceuticals					Assay Description Stromelysin inhibitory activity is based on the hydrolysis of substance P by recombinant human stromelysin to generate a fragment, substance P 7-11, ...				J Med Chem 40: 2525-32 (1997) Article DOI: 10.1021/jm960871c BindingDB Entry DOI: 10.7270/Q2MW2FC7
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