BDBM13135 (2R,3S)-2-[benzyl(4-methoxybenzene)sulfonamido]-N-hydroxy-3-methylpentanamide::CGS 27023A Analog 67

SMILES: CCC(C)[C@@H](N(Cc1ccccc1)S(=O)(=O)c1ccc(OC)cc1)C(=O)NO

InChI Key: InChIKey=WMGKYBYVBSCKIZ-XCWJXAQQSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 13135   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Stromelysin-1 (Homo sapiens (Human))	BDBM13135 ((2R,3S)-2-[benzyl(4-methoxybenzene)sulfonamido]-N-...) Show SMILES CCC(C)[C@@H](N(Cc1ccccc1)S(=O)(=O)c1ccc(OC)cc1)C(=O)NO |r| Show InChI InChI=1S/C20H26N2O5S/c1-4-15(2)19(20(23)21-24)22(14-16-8-6-5-7-9-16)28(25,26)18-12-10-17(27-3)11-13-18/h5-13,15,19,24H,4,14H2,1-3H3,(H,21,23)/t15?,19-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	39	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Pharmaceuticals					Assay Description Stromelysin inhibitory activity is based on the hydrolysis of substance P by recombinant human stromelysin to generate a fragment, substance P 7-11, ...				J Med Chem 40: 2525-32 (1997) Article DOI: 10.1021/jm960871c BindingDB Entry DOI: 10.7270/Q2MW2FC7
					More data for this Ligand-Target Pair