BDBM132076 US8841453, 7
SMILES: CC(=O)O[C@@]12CCN([C@@H]1N(C(C)=O)c1ccc(OC(=O)NCCCCCCNc3c4CCCCc4nc4ccccc34)cc21)C(C)=O
InChI Key: InChIKey=JCZCGQLHQOCURC-QZCRLSDHSA-N
Data: 2 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Cholinesterases (Homo sapiens (Human)) | BDBM132076 (US8841453, 7) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 3.15 | n/a | n/a | n/a | n/a | n/a | n/a |
Uniwersytet Warszawski; Centrum Medyczne Ksztalcenia Podyplomowego US Patent | Assay Description The biological activity of the compounds of general formula (I) towards the cholinesterase inhibition was evaluated using Ellman's method (Ellman, G.... | US Patent US8841453 (2014) BindingDB Entry DOI: 10.7270/Q2W957VS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Acetylcholinesterase (Homo sapiens (Human)) | BDBM132076 (US8841453, 7) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 36.8 | n/a | n/a | n/a | n/a | n/a | n/a |
Uniwersytet Warszawski; Centrum Medyczne Ksztalcenia Podyplomowego US Patent | Assay Description The biological activity of the compounds of general formula (I) towards the cholinesterase inhibition was evaluated using Ellman's method (Ellman, G.... | US Patent US8841453 (2014) BindingDB Entry DOI: 10.7270/Q2W957VS | |||||||||||
More data for this Ligand-Target Pair |