BDBM13225 2-[[(tert-Butyloxy)carbonyl]-amino]-4-methyl-N-phenyl-1,3-thiazole-5-carboxamide::BMS-354825 tert-Butoxycarbamate Analog 5f::CHEMBL424450::tert-butyl N-[4-methyl-5-(phenylcarbamoyl)-1,3-thiazol-2-yl]carbamate

SMILES: Cc1nc(NC(=O)OC(C)(C)C)sc1C(=O)Nc1ccccc1

InChI Key: InChIKey=ICOPXDXFUPQJCR-UHFFFAOYSA-N

Data: 1 IC50  1 Other

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 13225   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase LCK (Mus musculus)	BDBM13225 (2-[[(tert-Butyloxy)carbonyl]-amino]-4-methyl-N-phe...) Show SMILES Cc1nc(NC(=O)OC(C)(C)C)sc1C(=O)Nc1ccccc1 Show InChI InChI=1S/C16H19N3O3S/c1-10-12(13(20)18-11-8-6-5-7-9-11)23-14(17-10)19-15(21)22-16(2,3)4/h5-9H,1-4H3,(H,18,20)(H,17,19,21)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description In vitro inhibition of murine Lck kinase.				Bioorg Med Chem Lett 13: 4007-10 (2003) BindingDB Entry DOI: 10.7270/Q2CC103J
					More data for this Ligand-Target Pair
Lck (Mus musculus)	BDBM13225 (2-[[(tert-Butyloxy)carbonyl]-amino]-4-methyl-N-phe...) Show SMILES Cc1nc(NC(=O)OC(C)(C)C)sc1C(=O)Nc1ccccc1 Show InChI InChI=1S/C16H19N3O3S/c1-10-12(13(20)18-11-8-6-5-7-9-11)23-14(17-10)19-15(21)22-16(2,3)4/h5-9H,1-4H3,(H,18,20)(H,17,19,21)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	n/a	n/a	n/a	7.0	22
Bristol-Myers Squibb Company					Assay Description IC50 is the inhibitor concentration, which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-33P] lab...				J Med Chem 49: 6819-32 (2006) Article DOI: 10.1021/jm060727j BindingDB Entry DOI: 10.7270/Q2QN6501
					More data for this Ligand-Target Pair