BDBM13253 5-N-(2-chloro-6-methylphenyl)-2-N-(furan-2-)-1,3-thiazole-2,5-diamido::BMS-354825 2-Carboxamido-4-hydrido-thiazole Analog 7u::CHEMBL128070::N-(2-Chloro-6-methylphenyl)-2-[(2-furanylcarbonyl)amino]-1,3-thiazole-5-carboxamide

SMILES: Cc1cccc(Cl)c1NC(=O)c1cnc(NC(=O)c2ccco2)s1

InChI Key: InChIKey=BFSDCMXBRNMKDG-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 13253   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase Lck (Homo sapiens (Human))	BDBM13253 (5-N-(2-chloro-6-methylphenyl)-2-N-(furan-2-)-1,3-t...) Show SMILES Cc1cccc(Cl)c1NC(=O)c1cnc(NC(=O)c2ccco2)s1 Show InChI InChI=1S/C16H12ClN3O3S/c1-9-4-2-5-10(17)13(9)19-15(22)12-8-18-16(24-12)20-14(21)11-6-3-7-23-11/h2-8H,1H3,(H,19,22)(H,18,20,21)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	3.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibitory activity of the compound human Lck(hLck) kinase				Bioorg Med Chem Lett 13: 4007-10 (2003) BindingDB Entry DOI: 10.7270/Q2CC103J
					More data for this Ligand-Target Pair
Tyrosine-protein kinase Lck (Homo sapiens (Human))	BDBM13253 (5-N-(2-chloro-6-methylphenyl)-2-N-(furan-2-)-1,3-t...) Show SMILES Cc1cccc(Cl)c1NC(=O)c1cnc(NC(=O)c2ccco2)s1 Show InChI InChI=1S/C16H12ClN3O3S/c1-9-4-2-5-10(17)13(9)19-15(22)12-8-18-16(24-12)20-14(21)11-6-3-7-23-11/h2-8H,1H3,(H,19,22)(H,18,20,21)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company					Assay Description IC50 is the inhibitor concentration, which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-33P] lab...				J Med Chem 49: 6819-32 (2006) Article DOI: 10.1021/jm060727j BindingDB Entry DOI: 10.7270/Q2QN6501
					More data for this Ligand-Target Pair