BDBM132860 US8846746, 130

SMILES: FC(F)(F)Oc1cccc(c1)-c1cc(NC(=O)[C@H]2CNC(=O)C2)nn1-c1ccccc1Cl

InChI Key: InChIKey=HOUQBYGSDZQEKK-CYBMUJFWSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 132860   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium/glucose cotransporter 1 (SGLT1) (Homo sapiens (Human))	BDBM132860 (US8846746, 130) Show SMILES FC(F)(F)Oc1cccc(c1)-c1cc(NC(=O)[C@H]2CNC(=O)C2)nn1-c1ccccc1Cl |r| Show InChI InChI=1S/C21H16ClF3N4O3/c22-15-6-1-2-7-16(15)29-17(12-4-3-5-14(8-12)32-21(23,24)25)10-18(28-29)27-20(31)13-9-19(30)26-11-13/h1-8,10,13H,9,11H2,(H,26,30)(H,27,28,31)/t13-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.30	n/a	n/a	n/a	n/a	n/a	37
Japan Tobacco Inc. US Patent					Assay Description The stable cell line expressing human SGLT1 was seeded at 5x104 cells/well on BioCoat Poly-D-Lysine 96 well plate with Lid (Becton Dickinson and Comp...				US Patent US8846746 (2014) BindingDB Entry DOI: 10.7270/Q27M06MJ
					More data for this Ligand-Target Pair