BDBM133200 US8846746, 523

SMILES: COc1ccc(F)c(c1)-n1nc(NC(=O)[C@@H]2CNC(=O)C2)cc1-c1cccc(CO[C@H](C)C(F)(F)F)c1

InChI Key: InChIKey=ZMWAXLVRSYJYLI-PBHICJAKSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 133200   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium/glucose cotransporter 1 (SGLT1) (Homo sapiens (Human))	BDBM133200 (US8846746, 523) Show SMILES COc1ccc(F)c(c1)-n1nc(NC(=O)[C@@H]2CNC(=O)C2)cc1-c1cccc(CO[C@H](C)C(F)(F)F)c1 |r| Show InChI InChI=1S/C25H24F4N4O4/c1-14(25(27,28)29)37-13-15-4-3-5-16(8-15)20-11-22(31-24(35)17-9-23(34)30-12-17)32-33(20)21-10-18(36-2)6-7-19(21)26/h3-8,10-11,14,17H,9,12-13H2,1-2H3,(H,30,34)(H,31,32,35)/t14-,17+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	2.15	n/a	n/a	n/a	n/a	n/a	37
Japan Tobacco Inc. US Patent					Assay Description The stable cell line expressing human SGLT1 was seeded at 5x104 cells/well on BioCoat Poly-D-Lysine 96 well plate with Lid (Becton Dickinson and Comp...				US Patent US8846746 (2014) BindingDB Entry DOI: 10.7270/Q27M06MJ
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