BDBM13331 N-tert-butyl-2-({6-isocyano-1-[(1-methyl-1H-imidazol-5-yl)methyl]-1,2,3,4-tetrahydroquinolin-3-yl}(pyridine-2-)sulfonamido)acetamide::N1-(tert-butyl)-N2-{6-isocyano-1-[(1-methyl-1H-imidazol-5-yl)methyl]-1,2,3,4-tetrahydroquinolin-3-yl}-N2-(pyridin-2-ylsulfonyl)glycinamide::tetrahydroquinoline (THQ)-based inhibitor 4m

SMILES: Cn1cncc1CN1CC(Cc2cc(ccc12)[N+]#[C-])N(CC(=O)NC(C)(C)C)S(=O)(=O)c1ccccn1

InChI Key: InChIKey=GZCBQVAEYLEZKD-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 13331   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein farnesyltransferase (Rattus norvegicus (rat))	BDBM13331 (N-tert-butyl-2-({6-isocyano-1-[(1-methyl-1H-imidaz...) Show SMILES Cn1cncc1CN1CC(Cc2cc(ccc12)[N+]#[C-])N(CC(=O)NC(C)(C)C)S(=O)(=O)c1ccccn1 Show InChI InChI=1S/C26H31N7O3S/c1-26(2,3)30-24(34)17-33(37(35,36)25-8-6-7-11-29-25)21-13-19-12-20(27-4)9-10-23(19)32(15-21)16-22-14-28-18-31(22)5/h6-12,14,18,21H,13,15-17H2,1-3,5H3,(H,30,34)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.80	n/a	n/a	n/a	n/a	n/a	n/a
University of Washington at Seattle					Assay Description Assays for PFT activity were performed with a PFT-specific scintillation assay (SPA) kit (Amersham Biosciences, Piscataway, NJ). IC50 values were cal...				J Med Chem 48: 3704-13 (2005) Article DOI: 10.1021/jm0491039 BindingDB Entry DOI: 10.7270/Q2BC3WSQ
					More data for this Ligand-Target Pair
Protein Farnesyltransferase (PFT) (Plasmodium falciparum (malaria parasite P. falcipa...)	BDBM13331 (N-tert-butyl-2-({6-isocyano-1-[(1-methyl-1H-imidaz...) Show SMILES Cn1cncc1CN1CC(Cc2cc(ccc12)[N+]#[C-])N(CC(=O)NC(C)(C)C)S(=O)(=O)c1ccccn1 Show InChI InChI=1S/C26H31N7O3S/c1-26(2,3)30-24(34)17-33(37(35,36)25-8-6-7-11-29-25)21-13-19-12-20(27-4)9-10-23(19)32(15-21)16-22-14-28-18-31(22)5/h6-12,14,18,21H,13,15-17H2,1-3,5H3,(H,30,34)	KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.40	n/a	n/a	n/a	n/a	7.5	37
University of Washington at Seattle					Assay Description Assays for PFT activity were performed with a PFT-specific scintillation assay (SPA) kit (Amersham Biosciences, Piscataway, NJ). IC50 values were cal...				J Med Chem 48: 3704-13 (2005) Article DOI: 10.1021/jm0491039 BindingDB Entry DOI: 10.7270/Q2BC3WSQ
					More data for this Ligand-Target Pair