BDBM13360 (2S)-2-[(2R)-2-[(2S)-2-[(2R)-2-amino-3-sulfanylpropanamido]-3-methylbutanamido]-3-(2,4-dimethylphenyl)propanamido]-4-(methylsulfanyl)butanoic acid::CAAX Analogue 3::Compound III

SMILES: CSCC[C@H](NC(=O)[C@@H](Cc1ccc(C)cc1C)NC(=O)[C@@H](NC(=O)[C@@H](N)CS)C(C)C)C(O)=O

InChI Key: InChIKey=OSCYYRDQLWFHKF-HAGHYFMRSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 13360   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein farnesyltransferase (Bos taurus (bovine))	BDBM13360 ((2S)-2-[(2R)-2-[(2S)-2-[(2R)-2-amino-3-sulfanylpro...) Show SMILES CSCC[C@H](NC(=O)[C@@H](Cc1ccc(C)cc1C)NC(=O)[C@@H](NC(=O)[C@@H](N)CS)C(C)C)C(O)=O |r| Show InChI InChI=1S/C24H38N4O5S2/c1-13(2)20(28-21(29)17(25)12-34)23(31)27-19(11-16-7-6-14(3)10-15(16)4)22(30)26-18(24(32)33)8-9-35-5/h6-7,10,13,17-20,34H,8-9,11-12,25H2,1-5H3,(H,26,30)(H,27,31)(H,28,29)(H,32,33)/t17-,18-,19+,20-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.30E+3	n/a	n/a	n/a	n/a	7.5	37
Universita di Napoli Federico II					Assay Description Assays for PFT activity were performed with a PFT-specific scintillation assay (SPA) kit (Amersham Biosciences, Piscataway, NJ). IC50 values were cal...				J Med Chem 49: 1882-90 (2006) Article DOI: 10.1021/jm0506165 BindingDB Entry DOI: 10.7270/Q22V2DCH
					More data for this Ligand-Target Pair