BDBM13370 (2S)-2-[(2R)-3-(4-hydroxy-2,5-dimethylphenyl)-2-[(2S)-2-[(2R)-2-formamido-3-sulfanylpropanamido]-3-methylbutanamido]propanamido]-4-(methylsulfanyl)butanoic acid::CAAX Analogue 13::Compound XIII

SMILES: CSCC[C@H](NC(=O)[C@@H](Cc1cc(C)c(O)cc1C)NC(=O)[C@@H](NC(=O)[C@H](CS)NC=O)C(C)C)C(O)=O

InChI Key: InChIKey=FMCAFXHLMUOIGG-JTJHWIPRSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 13370   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein farnesyltransferase (Bos taurus (bovine))	BDBM13370 ((2S)-2-[(2R)-3-(4-hydroxy-2,5-dimethylphenyl)-2-[(...) Show SMILES CSCC[C@H](NC(=O)[C@@H](Cc1cc(C)c(O)cc1C)NC(=O)[C@@H](NC(=O)[C@H](CS)NC=O)C(C)C)C(O)=O |r| Show InChI InChI=1S/C25H38N4O7S2/c1-13(2)21(29-23(33)19(11-37)26-12-30)24(34)28-18(10-16-8-15(4)20(31)9-14(16)3)22(32)27-17(25(35)36)6-7-38-5/h8-9,12-13,17-19,21,31,37H,6-7,10-11H2,1-5H3,(H,26,30)(H,27,32)(H,28,34)(H,29,33)(H,35,36)/t17-,18+,19-,21-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.02E+4	n/a	n/a	n/a	n/a	7.5	37
Universita di Napoli Federico II					Assay Description Assays for PFT activity were performed with a PFT-specific scintillation assay (SPA) kit (Amersham Biosciences, Piscataway, NJ). IC50 values were cal...				J Med Chem 49: 1882-90 (2006) Article DOI: 10.1021/jm0506165 BindingDB Entry DOI: 10.7270/Q22V2DCH
					More data for this Ligand-Target Pair