BDBM134147 US8846689, 149

SMILES: COc1cc(C(=O)NC2CCN(CC2)C2CCOCC2)c(C)cc1Nc1ncc(Cl)c(Oc2cccc3CN(C)C(=O)c23)n1

InChI Key: InChIKey=KFFUAVXIEVRHCN-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 134147   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Focal adhesion kinase 1 (Homo sapiens (Human))	BDBM134147 (US8846689, 149) Show SMILES COc1cc(C(=O)NC2CCN(CC2)C2CCOCC2)c(C)cc1Nc1ncc(Cl)c(Oc2cccc3CN(C)C(=O)c23)n1 Show InChI InChI=1S/C32H37ClN6O5/c1-19-15-25(27(42-3)16-23(19)29(40)35-21-7-11-39(12-8-21)22-9-13-43-14-10-22)36-32-34-17-24(33)30(37-32)44-26-6-4-5-20-18-38(2)31(41)28(20)26/h4-6,15-17,21-22H,7-14,18H2,1-3H3,(H,35,40)(H,34,36,37)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	7.5	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description This test uses active PTK2 enzyme (Invitrogen Code PV3832) and poly-Glu-Tyr (4:1, Sigma P-0275) as the kinase substrate. The kinase activity is detec...				US Patent US8846689 (2014) BindingDB Entry DOI: 10.7270/Q2BC3X7Z
					More data for this Ligand-Target Pair