BDBM134162 US8846689, 164

SMILES: CCN1CC[C@H](NC(=O)c2cc(OC)c(Nc3ncc(Cl)c(Oc4cccc5[C@H](C)N(C)C(=O)c45)n3)cc2F)[C@H](F)C1

InChI Key: InChIKey=NNOVURDJSCRJTF-RVHYNSKXSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 134162   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Focal adhesion kinase 1 (Homo sapiens (Human))	BDBM134162 (US8846689, 164) Show SMILES CCN1CC[C@H](NC(=O)c2cc(OC)c(Nc3ncc(Cl)c(Oc4cccc5[C@H](C)N(C)C(=O)c45)n3)cc2F)[C@H](F)C1 |r| Show InChI InChI=1S/C29H31ClF2N6O4/c1-5-38-10-9-21(20(32)14-38)34-26(39)17-11-24(41-4)22(12-19(17)31)35-29-33-13-18(30)27(36-29)42-23-8-6-7-16-15(2)37(3)28(40)25(16)23/h6-8,11-13,15,20-21H,5,9-10,14H2,1-4H3,(H,34,39)(H,33,35,36)/t15-,20+,21-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	7.5	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description This test uses active PTK2 enzyme (Invitrogen Code PV3832) and poly-Glu-Tyr (4:1, Sigma P-0275) as the kinase substrate. The kinase activity is detec...				US Patent US8846689 (2014) BindingDB Entry DOI: 10.7270/Q2BC3X7Z
					More data for this Ligand-Target Pair