null

SMILES: CO[C@H]1CN(C)CC[C@H]1NC(=O)c1cc(OC)c(Nc2ncc(Cl)c(Oc3cccc4c3C(=O)N(C)C4(C)C)n2)cc1C

InChI Key: InChIKey=LCNAAQOCPPIRBP-BWKNWUBXSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 134170   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Focal adhesion kinase 1 (Homo sapiens (Human))	BDBM134170 (US8846689, 172) Show SMILES CO[C@H]1CN(C)CC[C@H]1NC(=O)c1cc(OC)c(Nc2ncc(Cl)c(Oc3cccc4c3C(=O)N(C)C4(C)C)n2)cc1C |r| Show InChI InChI=1S/C31H37ClN6O5/c1-17-13-22(24(41-6)14-18(17)27(39)34-21-11-12-37(4)16-25(21)42-7)35-30-33-15-20(32)28(36-30)43-23-10-8-9-19-26(23)29(40)38(5)31(19,2)3/h8-10,13-15,21,25H,11-12,16H2,1-7H3,(H,34,39)(H,33,35,36)/t21-,25+/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	7.5	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description This test uses active PTK2 enzyme (Invitrogen Code PV3832) and poly-Glu-Tyr (4:1, Sigma P-0275) as the kinase substrate. The kinase activity is detec...				US Patent US8846689 (2014) BindingDB Entry DOI: 10.7270/Q2BC3X7Z
					More data for this Ligand-Target Pair