BDBM134191 US8846689, 193
SMILES: CN1Cc2cccc(Oc3nc(Nc4ccc(cc4C)C(=O)NC4CCN(C)CC4)ncc3C(F)(F)F)c2C1=O
InChI Key: InChIKey=ZIZWEURKTNQLCZ-UHFFFAOYSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Focal adhesion kinase 1 (Homo sapiens (Human)) | BDBM134191 (US8846689, 193) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 1 | n/a | n/a | n/a | n/a | 7.5 | n/a |
Boehringer Ingelheim International GmbH US Patent | Assay Description This test uses active PTK2 enzyme (Invitrogen Code PV3832) and poly-Glu-Tyr (4:1, Sigma P-0275) as the kinase substrate. The kinase activity is detec... | US Patent US8846689 (2014) BindingDB Entry DOI: 10.7270/Q2BC3X7Z | |||||||||||
More data for this Ligand-Target Pair |