Found 5 hits for monomerid = 134787 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kcal/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
1,3-beta-glucan synthase component GSC2
(Saccharomyces cerevisiae) | BDBM134787
(US8846698, 250)Show SMILES CC(C)n1cc(C(=O)c2cncc(NC(=O)Cc3ccc(Cl)cc3)c2)c2cnc(N)nc12 Show InChI InChI=1S/C23H21ClN6O2/c1-13(2)30-12-19(18-11-27-23(25)29-22(18)30)21(32)15-8-17(10-26-9-15)28-20(31)7-14-3-5-16(24)6-4-14/h3-6,8-13H,7H2,1-2H3,(H,28,31)(H2,25,27,29) | KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet 
| PC cid
PC sid
UniChem
Similars
| | 1.69E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
High affinity nerve growth factor receptor
(Homo sapiens (Human)) | BDBM134787
(US8846698, 250)Show SMILES CC(C)n1cc(C(=O)c2cncc(NC(=O)Cc3ccc(Cl)cc3)c2)c2cnc(N)nc12 Show InChI InChI=1S/C23H21ClN6O2/c1-13(2)30-12-19(18-11-27-23(25)29-22(18)30)21(32)15-8-17(10-26-9-15)28-20(31)7-14-3-5-16(24)6-4-14/h3-6,8-13H,7H2,1-2H3,(H,28,31)(H2,25,27,29) | PDB
MMDB
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| | n/a | n/a | 6 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
NT-3 growth factor receptor
(Homo sapiens (Human)) | BDBM134787
(US8846698, 250)Show SMILES CC(C)n1cc(C(=O)c2cncc(NC(=O)Cc3ccc(Cl)cc3)c2)c2cnc(N)nc12 Show InChI InChI=1S/C23H21ClN6O2/c1-13(2)30-12-19(18-11-27-23(25)29-22(18)30)21(32)15-8-17(10-26-9-15)28-20(31)7-14-3-5-16(24)6-4-14/h3-6,8-13H,7H2,1-2H3,(H,28,31)(H2,25,27,29) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| | n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
High affinity nerve growth factor receptor
(Homo sapiens (Human)) | BDBM134787
(US8846698, 250)Show SMILES CC(C)n1cc(C(=O)c2cncc(NC(=O)Cc3ccc(Cl)cc3)c2)c2cnc(N)nc12 Show InChI InChI=1S/C23H21ClN6O2/c1-13(2)30-12-19(18-11-27-23(25)29-22(18)30)21(32)15-8-17(10-26-9-15)28-20(31)7-14-3-5-16(24)6-4-14/h3-6,8-13H,7H2,1-2H3,(H,28,31)(H2,25,27,29) | PDB
MMDB
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | 3.48 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Limited
US Patent
| Assay Description
Isolated TRK Enzyme assays use the HTRF KinEASE-TK kit (Cisbio Cat# 62TK0PEJ) with recombinant His-tagged cytoplasmic domains of each TRK receptor so... |
US Patent US8846698 (2014)
BindingDB Entry DOI: 10.7270/Q2F47MTW |
More data for this
Ligand-Target Pair | |
BDNF/NT-3 growth factors receptor
(Homo sapiens (Human)) | BDBM134787
(US8846698, 250)Show SMILES CC(C)n1cc(C(=O)c2cncc(NC(=O)Cc3ccc(Cl)cc3)c2)c2cnc(N)nc12 Show InChI InChI=1S/C23H21ClN6O2/c1-13(2)30-12-19(18-11-27-23(25)29-22(18)30)21(32)15-8-17(10-26-9-15)28-20(31)7-14-3-5-16(24)6-4-14/h3-6,8-13H,7H2,1-2H3,(H,28,31)(H2,25,27,29) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| | n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
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