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BDBM135792 US8853242, 170

SMILES: Cc1cnc(-c2c(F)cccc2F)c2cc(ccc12)C(=O)N=C(N)N

InChI Key: InChIKey=MFSDVPDQRWLCTK-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 135792   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
5-hydroxytryptamine receptor 5A


(Homo sapiens (Human))		BDBM135792
PNG
(US8853242, 170)
Show SMILES Cc1cnc(-c2c(F)cccc2F)c2cc(ccc12)C(=O)N=C(N)N |(-3.33,-4.62,;-3.33,-3.08,;-4.67,-2.31,;-4.67,-.77,;-3.33,,;-3.33,1.54,;-4.67,2.31,;-6,1.54,;-4.67,3.85,;-3.33,4.62,;-2,3.85,;-2,2.31,;-.67,1.54,;-2,-.77,;-.67,,;.67,-.77,;.67,-2.31,;-.67,-3.08,;-2,-2.31,;2,,;2,1.54,;3.33,-.77,;4.67,,;6,-.77,;4.67,1.54,)|
Show InChI InChI=1S/C18H14F2N4O/c1-9-8-23-16(15-13(19)3-2-4-14(15)20)12-7-10(5-6-11(9)12)17(25)24-18(21)22/h2-8H,1H3,(H4,21,22,24,25)
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Similars
US Patent
 1.90 -11.9n/an/an/an/an/a7.525



Astellas Pharma Inc.

US Patent


Assay Description
A solution of the compound to be tested and 100 μM 5-CT (5-carboxamidetriptamine) in DMSO was added to a 96-well plate at 2 μl/well, suspen...

US Patent US8853242 (2014)


BindingDB Entry DOI: 10.7270/Q2NP2346
More data for this
Ligand-Target Pair