BDBM135796 US8853242, 211

SMILES: [#7]\[#6](-[#7])=[#7]\[#6](=O)-c1ccc2c(Cl)cnc(-c3ccc(F)cc3F)c2c1

InChI Key: InChIKey=RTCPHQATTMCCCB-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 135796   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 5A (Homo sapiens (Human))	BDBM135796 (US8853242, 211) Show SMILES [#7]\[#6](-[#7])=[#7]\[#6](=O)-c1ccc2c(Cl)cnc(-c3ccc(F)cc3F)c2c1 Show InChI InChI=1S/C17H11ClF2N4O/c18-13-7-23-15(11-4-2-9(19)6-14(11)20)12-5-8(1-3-10(12)13)16(25)24-17(21)22/h1-7H,(H4,21,22,24,25)	KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	2.30	-11.8	n/a	n/a	n/a	n/a	n/a	7.5	25
Astellas Pharma Inc. US Patent					Assay Description A solution of the compound to be tested and 100 μM 5-CT (5-carboxamidetriptamine) in DMSO was added to a 96-well plate at 2 μl/well, suspen...				US Patent US8853242 (2014) BindingDB Entry DOI: 10.7270/Q2NP2346
					More data for this Ligand-Target Pair