null

SMILES: CSC[C@@H](NCc1c[nH]c2c(O)ncnc12)[C@@H](O)CO

InChI Key: InChIKey=XZZAMLCSKGDMOZ-BDAKNGLRSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 136307   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Purine nucleoside phosphorylase (Plasmodium falciparum)	BDBM136307 (US8853224, 25) Show SMILES CSC[C@@H](NCc1c[nH]c2c(O)ncnc12)[C@@H](O)CO Show InChI InChI=1S/C12H18N4O3S/c1-20-5-8(9(18)4-17)13-2-7-3-14-11-10(7)15-6-16-12(11)19/h3,6,8-9,13-14,17-18H,2,4-5H2,1H3,(H,15,16,19)/t8-,9+/m1/s1	PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	1.30E+4	n/a	n/a	n/a	n/a	25
Industrial Research Limited; Albert Einstein College of Medicine of Yeshiva University US Patent					Assay Description The inhibitor dissociation constants reported in Table 1 below are for phosphorolysis of inosine by PNP and were based on reaction rates measurements...				US Patent US8853224 (2014) BindingDB Entry DOI: 10.7270/Q27H1H84
					More data for this Ligand-Target Pair
Purine nucleoside phosphorylase (Homo sapiens (Human))	BDBM136307 (US8853224, 25) Show SMILES CSC[C@@H](NCc1c[nH]c2c(O)ncnc12)[C@@H](O)CO Show InChI InChI=1S/C12H18N4O3S/c1-20-5-8(9(18)4-17)13-2-7-3-14-11-10(7)15-6-16-12(11)19/h3,6,8-9,13-14,17-18H,2,4-5H2,1H3,(H,15,16,19)/t8-,9+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	74	n/a	n/a	n/a	n/a	25
Industrial Research Limited; Albert Einstein College of Medicine of Yeshiva University US Patent					Assay Description The inhibitor dissociation constants reported in Table 1 below are for phosphorolysis of inosine by PNP and were based on reaction rates measurements...				US Patent US8853224 (2014) BindingDB Entry DOI: 10.7270/Q27H1H84
					More data for this Ligand-Target Pair