BDBM136308 US8853224, 26
SMILES: CSC[C@@H](NCc1c[nH]c2c1nc[nH]c2=O)[C@H](O)CO
InChI Key: InChIKey=XZZAMLCSKGDMOZ-RKDXNWHRSA-N
Data: 2 Kd
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Purine nucleoside phosphorylase (Plasmodium falciparum) | BDBM136308 (US8853224, 26) | PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | n/a | 1.00E+4 | n/a | n/a | n/a | n/a | 25 |
Industrial Research Limited; Albert Einstein College of Medicine of Yeshiva University US Patent | Assay Description The inhibitor dissociation constants reported in Table 1 below are for phosphorolysis of inosine by PNP and were based on reaction rates measurements... | US Patent US8853224 (2014) BindingDB Entry DOI: 10.7270/Q27H1H84 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Purine nucleoside phosphorylase (Homo sapiens (Human)) | BDBM136308 (US8853224, 26) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | n/a | 71 | n/a | n/a | n/a | n/a | 25 |
Industrial Research Limited; Albert Einstein College of Medicine of Yeshiva University US Patent | Assay Description The inhibitor dissociation constants reported in Table 1 below are for phosphorolysis of inosine by PNP and were based on reaction rates measurements... | US Patent US8853224 (2014) BindingDB Entry DOI: 10.7270/Q27H1H84 | |||||||||||
More data for this Ligand-Target Pair |