BDBM136316 US8859534, 2

SMILES: O=C(Nc1ccc(cc1)N1CCOCC1)c1cc2cccc(N3CCN(CCc4ccccn4)CC3)c2o1

InChI Key: InChIKey=XWUPROYFXZAWOD-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 136316   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 1B (5HT1B) (Cricetulus griseus (Chinese hamster) (Cricetulus b...)	BDBM136316 (US8859534, 2) Show SMILES O=C(Nc1ccc(cc1)N1CCOCC1)c1cc2cccc(N3CCN(CCc4ccccn4)CC3)c2o1 Show InChI InChI=1S/C30H33N5O3/c36-30(32-25-7-9-26(10-8-25)34-18-20-37-21-19-34)28-22-23-4-3-6-27(29(23)38-28)35-16-14-33(15-17-35)13-11-24-5-1-2-12-31-24/h1-10,12,22H,11,13-21H2,(H,32,36)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	1.10	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
Acturum Life Science AB US Patent					Assay Description Assays that were used to measure affinity of the compounds of the present invention for 5-HT1A and 5-HT1B receptors are described in J. Recept Signal...				US Patent US8859534 (2014) BindingDB Entry DOI: 10.7270/Q23R0RKV
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (5HT1A) (Cricetulus griseus (Chinese hamster) (Cricetulus b...)	BDBM136316 (US8859534, 2) Show SMILES O=C(Nc1ccc(cc1)N1CCOCC1)c1cc2cccc(N3CCN(CCc4ccccn4)CC3)c2o1 Show InChI InChI=1S/C30H33N5O3/c36-30(32-25-7-9-26(10-8-25)34-18-20-37-21-19-34)28-22-23-4-3-6-27(29(23)38-28)35-16-14-33(15-17-35)13-11-24-5-1-2-12-31-24/h1-10,12,22H,11,13-21H2,(H,32,36)	PDB KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	1.30	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
Acturum Life Science AB US Patent					Assay Description Assays that were used to measure affinity of the compounds of the present invention for 5-HT1A and 5-HT1B receptors are described in J. Recept Signal...				US Patent US8859534 (2014) BindingDB Entry DOI: 10.7270/Q23R0RKV
					More data for this Ligand-Target Pair