BDBM136362 US8859534, 48

SMILES: COc1cccnc1CCN1CCN(CC1)c1cccc2cc(oc12)C(=O)N(C)C

InChI Key: InChIKey=NSEIYIHZQRXMDM-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 136362   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 1A (5HT1A) (Cricetulus griseus (Chinese hamster) (Cricetulus b...)	BDBM136362 (US8859534, 48) Show SMILES COc1cccnc1CCN1CCN(CC1)c1cccc2cc(oc12)C(=O)N(C)C Show InChI InChI=1S/C23H28N4O3/c1-25(2)23(28)21-16-17-6-4-7-19(22(17)30-21)27-14-12-26(13-15-27)11-9-18-20(29-3)8-5-10-24-18/h4-8,10,16H,9,11-15H2,1-3H3	PDB KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	0.160	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
Acturum Life Science AB US Patent					Assay Description Assays that were used to measure affinity of the compounds of the present invention for 5-HT1A and 5-HT1B receptors are described in J. Recept Signal...				US Patent US8859534 (2014) BindingDB Entry DOI: 10.7270/Q23R0RKV
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1B (5HT1B) (Cricetulus griseus (Chinese hamster) (Cricetulus b...)	BDBM136362 (US8859534, 48) Show SMILES COc1cccnc1CCN1CCN(CC1)c1cccc2cc(oc12)C(=O)N(C)C Show InChI InChI=1S/C23H28N4O3/c1-25(2)23(28)21-16-17-6-4-7-19(22(17)30-21)27-14-12-26(13-15-27)11-9-18-20(29-3)8-5-10-24-18/h4-8,10,16H,9,11-15H2,1-3H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	7.70	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
Acturum Life Science AB US Patent					Assay Description Assays that were used to measure affinity of the compounds of the present invention for 5-HT1A and 5-HT1B receptors are described in J. Recept Signal...				US Patent US8859534 (2014) BindingDB Entry DOI: 10.7270/Q23R0RKV
					More data for this Ligand-Target Pair