BDBM136521 US8865714, 8
SMILES: Cn1cccc1C(=O)N1CCN(CC1)C(=N)Nc1ccc(cc1)N1CCC(CCn2cncn2)CC1
InChI Key: InChIKey=ZOZUGQNXLOUPOX-UHFFFAOYSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Prostaglandin D Synthase (Homo sapiens (Human)) | BDBM136521 (US8865714, 8) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 62 | n/a | n/a | n/a | n/a | 8.0 | 25 |
Taiho Pharmaceutical Co., Ltd. US Patent | Assay Description The test was carried out according to the method of Urade, Y. et al. (J. Biol. Chem., 262, 3820-3825, (1987)). More specifically, the reaction mixtur... | US Patent US8865714 (2014) BindingDB Entry DOI: 10.7270/Q2QF8RKC | |||||||||||
More data for this Ligand-Target Pair |