BDBM13670 3-Oxybenzamide 56::4-chloro-3-[2-(4-chlorophenyl)ethoxy]-5-methoxy-N-{[1-(pyridin-4-yl)piperidin-4-yl]methyl}benzamide

SMILES: COc1cc(cc(OCCc2ccc(Cl)cc2)c1Cl)C(=O)NCC1CCN(CC1)c1ccncc1

InChI Key: InChIKey=NDVCFINRSAXDMP-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 13670   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Coagulation factor X (Homo sapiens (Human))	BDBM13670 (3-Oxybenzamide 56 | 4-chloro-3-[2-(4-chlorophenyl)...) Show SMILES COc1cc(cc(OCCc2ccc(Cl)cc2)c1Cl)C(=O)NCC1CCN(CC1)c1ccncc1 Show InChI InChI=1S/C27H29Cl2N3O3/c1-34-24-16-21(17-25(26(24)29)35-15-10-19-2-4-22(28)5-3-19)27(33)31-18-20-8-13-32(14-9-20)23-6-11-30-12-7-23/h2-7,11-12,16-17,20H,8-10,13-15,18H2,1H3,(H,31,33)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	25	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Aventis Pharma Deutschland GmbH					Assay Description The inhibitory effect of test compound for human fXa was determined by using the chromogenic substrates S-2765. The hydrolysis rates of chromogenic s...				J Med Chem 48: 3290-312 (2005) Article DOI: 10.1021/jm049187l BindingDB Entry DOI: 10.7270/Q28C9THZ
					More data for this Ligand-Target Pair
Prothrombin (Homo sapiens (Human))	BDBM13670 (3-Oxybenzamide 56 | 4-chloro-3-[2-(4-chlorophenyl)...) Show SMILES COc1cc(cc(OCCc2ccc(Cl)cc2)c1Cl)C(=O)NCC1CCN(CC1)c1ccncc1 Show InChI InChI=1S/C27H29Cl2N3O3/c1-34-24-16-21(17-25(26(24)29)35-15-10-19-2-4-22(28)5-3-19)27(33)31-18-20-8-13-32(14-9-20)23-6-11-30-12-7-23/h2-7,11-12,16-17,20H,8-10,13-15,18H2,1H3,(H,31,33)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	3.73E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Aventis Pharma Deutschland GmbH					Assay Description The inhibitory effect of test compound for human thrombin was determined by using the chromogenic substrates S-2366. The hydrolysis rates of chromoge...				J Med Chem 48: 3290-312 (2005) Article DOI: 10.1021/jm049187l BindingDB Entry DOI: 10.7270/Q28C9THZ
					More data for this Ligand-Target Pair