BDBM136704 US8865655, 16

SMILES: CC(C)[C@H]1NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@@H](C)NC(=O)C[C@H](OC(=O)CNC1=O)\C=C\CCS

InChI Key: InChIKey=CWPIKVMJGSLKKO-KJOPYZGFSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 136704   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone deacetylase 1 (Homo sapiens (Human))	BDBM136704 (US8865655, 16) Show SMILES CC(C)[C@H]1NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@@H](C)NC(=O)C[C@H](OC(=O)CNC1=O)\C=C\CCS |r| Show InChI InChI=1S/C26H36N4O6S/c1-16(2)23-26(35)27-15-22(32)36-19(11-7-8-12-37)14-21(31)28-17(3)24(33)29-20(25(34)30-23)13-18-9-5-4-6-10-18/h4-7,9-11,16-17,19-20,23,37H,8,12-15H2,1-3H3,(H,27,35)(H,28,31)(H,29,33)(H,30,34)/b11-7+/t17-,19-,20-,23-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	47	n/a	n/a	n/a	n/a	n/a	25
Karus Therapeutics Limited US Patent					Assay Description In vitro HDAC assays were performed using a HDAC fluorescent activity assay kit (Biomol, UK) according to the manufacturer's instructions. Compounds ...				US Patent US8865655 (2014) BindingDB Entry DOI: 10.7270/Q2Z036V4
					More data for this Ligand-Target Pair