BDBM13874 1-[(3-carbamimidoylphenyl)methyl]-N-{[3-fluoro-5-(trifluoromethyl)phenyl]methyl}-4-hydroxy-1H-indole-2-carboxamide::3-amidinobenzylindole carboxamide 59

SMILES: NC(=N)c1cccc(Cn2c(cc3c(O)cccc23)C(=O)NCc2cc(F)cc(c2)C(F)(F)F)c1

InChI Key: InChIKey=GQXDHJRJUQVDDX-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 13874   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Coagulation factor X (Homo sapiens (Human))	BDBM13874 (1-[(3-carbamimidoylphenyl)methyl]-N-{[3-fluoro-5-(...) Show SMILES NC(=N)c1cccc(Cn2c(cc3c(O)cccc23)C(=O)NCc2cc(F)cc(c2)C(F)(F)F)c1 Show InChI InChI=1S/C25H20F4N4O2/c26-18-9-15(8-17(10-18)25(27,28)29)12-32-24(35)21-11-19-20(5-2-6-22(19)34)33(21)13-14-3-1-4-16(7-14)23(30)31/h1-11,34H,12-13H2,(H3,30,31)(H,32,35)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	39	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Aventis Pharma Deutschland GmbH					Assay Description The inhibitory effect of test compound for human fXa was determined by using the chromogenic substrates S-2765. The hydrolysis rates of chromogenic s...				J Med Chem 45: 2749-69 (2002) Article DOI: 10.1021/jm0111346 BindingDB Entry DOI: 10.7270/Q27H1GTW
					More data for this Ligand-Target Pair
Prothrombin (Homo sapiens (Human))	BDBM13874 (1-[(3-carbamimidoylphenyl)methyl]-N-{[3-fluoro-5-(...) Show SMILES NC(=N)c1cccc(Cn2c(cc3c(O)cccc23)C(=O)NCc2cc(F)cc(c2)C(F)(F)F)c1 Show InChI InChI=1S/C25H20F4N4O2/c26-18-9-15(8-17(10-18)25(27,28)29)12-32-24(35)21-11-19-20(5-2-6-22(19)34)33(21)13-14-3-1-4-16(7-14)23(30)31/h1-11,34H,12-13H2,(H3,30,31)(H,32,35)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	1.71E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Aventis Pharma Deutschland GmbH					Assay Description The inhibitory effect of test compound for human thrombin was determined by using the chromogenic substrates S-2366. The hydrolysis rates of chromoge...				J Med Chem 45: 2749-69 (2002) Article DOI: 10.1021/jm0111346 BindingDB Entry DOI: 10.7270/Q27H1GTW
					More data for this Ligand-Target Pair