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BDBM13877 1-[(3-carbamimidoylphenyl)methyl]-4-hydroxy-N-[(3-iodophenyl)methyl]-1H-indole-2-carboxamide::3-amidinobenzylindole carboxamide 62

SMILES: NC(=N)c1cccc(Cn2c(cc3c(O)cccc23)C(=O)NCc2cccc(I)c2)c1

InChI Key: InChIKey=UVACBIWKEUYYBF-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 13877   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Coagulation factor X


(Homo sapiens (Human))
BDBM13877
PNG
(1-[(3-carbamimidoylphenyl)methyl]-4-hydroxy-N-[(3-...)
Show SMILES NC(=N)c1cccc(Cn2c(cc3c(O)cccc23)C(=O)NCc2cccc(I)c2)c1
Show InChI InChI=1S/C24H21IN4O2/c25-18-7-2-4-15(11-18)13-28-24(31)21-12-19-20(8-3-9-22(19)30)29(21)14-16-5-1-6-17(10-16)23(26)27/h1-12,30H,13-14H2,(H3,26,27)(H,28,31)
PDB
MMDB

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PC cid
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42n/an/an/an/an/an/an/an/a



Aventis Pharma Deutschland GmbH



Assay Description
The inhibitory effect of test compound for human fXa was determined by using the chromogenic substrates S-2765. The hydrolysis rates of chromogenic s...


J Med Chem 45: 2749-69 (2002)


BindingDB Entry DOI: 10.7270/Q27H1GTW
More data for this
Ligand-Target Pair