null

SMILES: Cc1cc(CNC(=O)c2cc3c(O)cccc3n2Cc2cccc(c2)C(N)=N)cc(c1)C(F)(F)F

InChI Key: InChIKey=KGJMNJQHRNGVAG-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 13880   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Coagulation factor X (Homo sapiens (Human))	BDBM13880 (1-[(3-carbamimidoylphenyl)methyl]-4-hydroxy-N-{[3-...) Show SMILES Cc1cc(CNC(=O)c2cc3c(O)cccc3n2Cc2cccc(c2)C(N)=N)cc(c1)C(F)(F)F Show InChI InChI=1S/C26H23F3N4O2/c1-15-8-17(11-19(9-15)26(27,28)29)13-32-25(35)22-12-20-21(6-3-7-23(20)34)33(22)14-16-4-2-5-18(10-16)24(30)31/h2-12,34H,13-14H2,1H3,(H3,30,31)(H,32,35)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	13	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Aventis Pharma Deutschland GmbH					Assay Description The inhibitory effect of test compound for human fXa was determined by using the chromogenic substrates S-2765. The hydrolysis rates of chromogenic s...				J Med Chem 45: 2749-69 (2002) Article DOI: 10.1021/jm0111346 BindingDB Entry DOI: 10.7270/Q27H1GTW
					More data for this Ligand-Target Pair
Prothrombin (Homo sapiens (Human))	BDBM13880 (1-[(3-carbamimidoylphenyl)methyl]-4-hydroxy-N-{[3-...) Show SMILES Cc1cc(CNC(=O)c2cc3c(O)cccc3n2Cc2cccc(c2)C(N)=N)cc(c1)C(F)(F)F Show InChI InChI=1S/C26H23F3N4O2/c1-15-8-17(11-19(9-15)26(27,28)29)13-32-25(35)22-12-20-21(6-3-7-23(20)34)33(22)14-16-4-2-5-18(10-16)24(30)31/h2-12,34H,13-14H2,1H3,(H3,30,31)(H,32,35)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	480	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Aventis Pharma Deutschland GmbH					Assay Description The inhibitory effect of test compound for human thrombin was determined by using the chromogenic substrates S-2366. The hydrolysis rates of chromoge...				J Med Chem 45: 2749-69 (2002) Article DOI: 10.1021/jm0111346 BindingDB Entry DOI: 10.7270/Q27H1GTW
					More data for this Ligand-Target Pair