BDBM139285 US8614223, 62::US8614223, 66

SMILES: C[C@@H](Nc1ncc(cn1)C(=O)NO)c1ccccc1

InChI Key: InChIKey=GISXYSUVYKFPRD-SECBINFHSA-N

Data: 8 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 139285   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone deacetylase 1 (Homo sapiens (Human))	BDBM139285 (US8614223, 62 | US8614223, 66) Show SMILES C[C@@H](Nc1ncc(cn1)C(=O)NO)c1ccccc1 |r| Show InChI InChI=1S/C13H14N4O2/c1-9(10-5-3-2-4-6-10)16-13-14-7-11(8-15-13)12(18)17-19/h2-9,19H,1H3,(H,17,18)(H,14,15,16)/t9-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	35	n/a	n/a	n/a	n/a	7.4	25
Acetylon Pharmaceuticals, Inc. US Patent					Assay Description Compounds for testing were diluted in DMSO to 50 fold the final concentration and a ten point three fold dilution series was made. The compounds were...				US Patent US8614223 (2013) BindingDB Entry DOI: 10.7270/Q2B27T00
					More data for this Ligand-Target Pair
Histone deacetylase 1 (Homo sapiens (Human))	BDBM139285 (US8614223, 62 | US8614223, 66) Show SMILES C[C@@H](Nc1ncc(cn1)C(=O)NO)c1ccccc1 |r| Show InChI InChI=1S/C13H14N4O2/c1-9(10-5-3-2-4-6-10)16-13-14-7-11(8-15-13)12(18)17-19/h2-9,19H,1H3,(H,17,18)(H,14,15,16)/t9-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	39	n/a	n/a	n/a	n/a	7.4	25
Acetylon Pharmaceuticals, Inc. US Patent					Assay Description Compounds for testing were diluted in DMSO to 50 fold the final concentration and a ten point three fold dilution series was made. The compounds were...				US Patent US8614223 (2013) BindingDB Entry DOI: 10.7270/Q2B27T00
					More data for this Ligand-Target Pair
Histone deacetylase 2 (Homo sapiens (Human))	BDBM139285 (US8614223, 62 | US8614223, 66) Show SMILES C[C@@H](Nc1ncc(cn1)C(=O)NO)c1ccccc1 |r| Show InChI InChI=1S/C13H14N4O2/c1-9(10-5-3-2-4-6-10)16-13-14-7-11(8-15-13)12(18)17-19/h2-9,19H,1H3,(H,17,18)(H,14,15,16)/t9-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	56	n/a	n/a	n/a	n/a	7.4	25
Acetylon Pharmaceuticals, Inc. US Patent					Assay Description Compounds for testing were diluted in DMSO to 50 fold the final concentration and a ten point three fold dilution series was made. The compounds were...				US Patent US8614223 (2013) BindingDB Entry DOI: 10.7270/Q2B27T00
					More data for this Ligand-Target Pair
Cereblon/Histone deacetylase 6 (Homo sapiens (Human))	BDBM139285 (US8614223, 62 | US8614223, 66) Show SMILES C[C@@H](Nc1ncc(cn1)C(=O)NO)c1ccccc1 |r| Show InChI InChI=1S/C13H14N4O2/c1-9(10-5-3-2-4-6-10)16-13-14-7-11(8-15-13)12(18)17-19/h2-9,19H,1H3,(H,17,18)(H,14,15,16)/t9-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	7.4	25
Acetylon Pharmaceuticals, Inc. US Patent					Assay Description Compounds for testing were diluted in DMSO to 50 fold the final concentration and a ten point three fold dilution series was made. The compounds were...				US Patent US8614223 (2013) BindingDB Entry DOI: 10.7270/Q2B27T00
					More data for this Ligand-Target Pair
Histone deacetylase 3 (Homo sapiens (Human))	BDBM139285 (US8614223, 62 | US8614223, 66) Show SMILES C[C@@H](Nc1ncc(cn1)C(=O)NO)c1ccccc1 |r| Show InChI InChI=1S/C13H14N4O2/c1-9(10-5-3-2-4-6-10)16-13-14-7-11(8-15-13)12(18)17-19/h2-9,19H,1H3,(H,17,18)(H,14,15,16)/t9-/m1/s1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	55	n/a	n/a	n/a	n/a	7.4	25
Acetylon Pharmaceuticals, Inc. US Patent					Assay Description Compounds for testing were diluted in DMSO to 50 fold the final concentration and a ten point three fold dilution series was made. The compounds were...				US Patent US8614223 (2013) BindingDB Entry DOI: 10.7270/Q2B27T00
					More data for this Ligand-Target Pair
Histone deacetylase 3 (Homo sapiens (Human))	BDBM139285 (US8614223, 62 | US8614223, 66) Show SMILES C[C@@H](Nc1ncc(cn1)C(=O)NO)c1ccccc1 |r| Show InChI InChI=1S/C13H14N4O2/c1-9(10-5-3-2-4-6-10)16-13-14-7-11(8-15-13)12(18)17-19/h2-9,19H,1H3,(H,17,18)(H,14,15,16)/t9-/m1/s1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	47	n/a	n/a	n/a	n/a	7.4	25
Acetylon Pharmaceuticals, Inc. US Patent					Assay Description Compounds for testing were diluted in DMSO to 50 fold the final concentration and a ten point three fold dilution series was made. The compounds were...				US Patent US8614223 (2013) BindingDB Entry DOI: 10.7270/Q2B27T00
					More data for this Ligand-Target Pair
Cereblon/Histone deacetylase 6 (Homo sapiens (Human))	BDBM139285 (US8614223, 62 | US8614223, 66) Show SMILES C[C@@H](Nc1ncc(cn1)C(=O)NO)c1ccccc1 |r| Show InChI InChI=1S/C13H14N4O2/c1-9(10-5-3-2-4-6-10)16-13-14-7-11(8-15-13)12(18)17-19/h2-9,19H,1H3,(H,17,18)(H,14,15,16)/t9-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	7.4	25
Acetylon Pharmaceuticals, Inc. US Patent					Assay Description Compounds for testing were diluted in DMSO to 50 fold the final concentration and a ten point three fold dilution series was made. The compounds were...				US Patent US8614223 (2013) BindingDB Entry DOI: 10.7270/Q2B27T00
					More data for this Ligand-Target Pair
Histone deacetylase 2 (Homo sapiens (Human))	BDBM139285 (US8614223, 62 | US8614223, 66) Show SMILES C[C@@H](Nc1ncc(cn1)C(=O)NO)c1ccccc1 |r| Show InChI InChI=1S/C13H14N4O2/c1-9(10-5-3-2-4-6-10)16-13-14-7-11(8-15-13)12(18)17-19/h2-9,19H,1H3,(H,17,18)(H,14,15,16)/t9-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	39	n/a	n/a	n/a	n/a	7.4	25
Acetylon Pharmaceuticals, Inc. US Patent					Assay Description Compounds for testing were diluted in DMSO to 50 fold the final concentration and a ten point three fold dilution series was made. The compounds were...				US Patent US8614223 (2013) BindingDB Entry DOI: 10.7270/Q2B27T00
					More data for this Ligand-Target Pair