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SMILES: CCN(CC)C(=O)c1cccc(c1)N1CCc2nc(N)ncc2C1

InChI Key: InChIKey=PKVUVWYYDGDERJ-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 139561   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM139561 (US8889870, 21 | US9388176, 21 | US9820989, 21) Show SMILES CCN(CC)C(=O)c1cccc(c1)N1CCc2nc(N)ncc2C1 Show InChI InChI=1S/C18H23N5O/c1-3-22(4-2)17(24)13-6-5-7-15(10-13)23-9-8-16-14(12-23)11-20-18(19)21-16/h5-7,10-11H,3-4,8-9,12H2,1-2H3,(H2,19,20,21)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ALLERGAN, INC. US Patent					Assay Description Biochemical PDGFRβ kinase assays were performed in 96 well microliter plates that were coated overnight with 75 μg of poly-Glu-Tyr (4:1) in...				US Patent US9820989 (2017) BindingDB Entry DOI: 10.7270/Q2TT4T6G
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM139561 (US8889870, 21 | US9388176, 21 | US9820989, 21) Show SMILES CCN(CC)C(=O)c1cccc(c1)N1CCc2nc(N)ncc2C1 Show InChI InChI=1S/C18H23N5O/c1-3-22(4-2)17(24)13-6-5-7-15(10-13)23-9-8-16-14(12-23)11-20-18(19)21-16/h5-7,10-11H,3-4,8-9,12H2,1-2H3,(H2,19,20,21)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	1.25E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ALLERGAN, INC. US Patent					Assay Description Biochemical KDR kinase assays were performed in 96 well microliter plates that were coated overnight with 75 μg/well of poly-Glu-Tyr (4:1) in 10...				US Patent US9820989 (2017) BindingDB Entry DOI: 10.7270/Q2TT4T6G
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM139561 (US8889870, 21 | US9388176, 21 | US9820989, 21) Show SMILES CCN(CC)C(=O)c1cccc(c1)N1CCc2nc(N)ncc2C1 Show InChI InChI=1S/C18H23N5O/c1-3-22(4-2)17(24)13-6-5-7-15(10-13)23-9-8-16-14(12-23)11-20-18(19)21-16/h5-7,10-11H,3-4,8-9,12H2,1-2H3,(H2,19,20,21)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.25E+3	n/a	n/a	n/a	n/a	7.4	30
ALLERGAN, INC. US Patent					Assay Description Biochemical KDR kinase assays were performed in 96 well microliter plates that were coated overnight with 75 μg/well of poly-Glu-Tyr (4:1) in 10 m...				US Patent US9388176 (2016) BindingDB Entry DOI: 10.7270/Q2TQ60DZ
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM139561 (US8889870, 21 | US9388176, 21 | US9820989, 21) Show SMILES CCN(CC)C(=O)c1cccc(c1)N1CCc2nc(N)ncc2C1 Show InChI InChI=1S/C18H23N5O/c1-3-22(4-2)17(24)13-6-5-7-15(10-13)23-9-8-16-14(12-23)11-20-18(19)21-16/h5-7,10-11H,3-4,8-9,12H2,1-2H3,(H2,19,20,21)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.25E+3	n/a	n/a	n/a	n/a	7.4	n/a
Allergan, Inc. US Patent					Assay Description Biochemical KDR kinase assays were performed in 96 well microliter plates that were coated overnight with 75 .mu.g/well of poly-Glu-Tyr (4:1) in 10 m...				US Patent US8889870 (2014) BindingDB Entry DOI: 10.7270/Q25B0158
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM139561 (US8889870, 21 | US9388176, 21 | US9820989, 21) Show SMILES CCN(CC)C(=O)c1cccc(c1)N1CCc2nc(N)ncc2C1 Show InChI InChI=1S/C18H23N5O/c1-3-22(4-2)17(24)13-6-5-7-15(10-13)23-9-8-16-14(12-23)11-20-18(19)21-16/h5-7,10-11H,3-4,8-9,12H2,1-2H3,(H2,19,20,21)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	7.4	30
ALLERGAN, INC. US Patent					Assay Description Biochemical PDGFRβ kinase assays were performed in 96 well microliter plates that were coated overnight with 75 μg of poly-Glu-Tyr (4:1) in 1...				US Patent US9388176 (2016) BindingDB Entry DOI: 10.7270/Q2TQ60DZ
					More data for this Ligand-Target Pair