null

SMILES: COC(=O)CNC(=O)c1cncc2CN(CCc12)c1cccc(c1)C(=O)Nc1cccc(c1)C(C)C

InChI Key: InChIKey=KFYUPVJUHVUEPF-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 139626   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM139626 (US8889870, 174 | US9388176, 174 | US9820989, 174) Show SMILES COC(=O)CNC(=O)c1cncc2CN(CCc12)c1cccc(c1)C(=O)Nc1cccc(c1)C(C)C Show InChI InChI=1S/C28H30N4O4/c1-18(2)19-6-4-8-22(12-19)31-27(34)20-7-5-9-23(13-20)32-11-10-24-21(17-32)14-29-15-25(24)28(35)30-16-26(33)36-3/h4-9,12-15,18H,10-11,16-17H2,1-3H3,(H,30,35)(H,31,34)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	49	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ALLERGAN, INC. US Patent					Assay Description Biochemical KDR kinase assays were performed in 96 well microliter plates that were coated overnight with 75 μg/well of poly-Glu-Tyr (4:1) in 10...				US Patent US9820989 (2017) BindingDB Entry DOI: 10.7270/Q2TT4T6G
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM139626 (US8889870, 174 | US9388176, 174 | US9820989, 174) Show SMILES COC(=O)CNC(=O)c1cncc2CN(CCc12)c1cccc(c1)C(=O)Nc1cccc(c1)C(C)C Show InChI InChI=1S/C28H30N4O4/c1-18(2)19-6-4-8-22(12-19)31-27(34)20-7-5-9-23(13-20)32-11-10-24-21(17-32)14-29-15-25(24)28(35)30-16-26(33)36-3/h4-9,12-15,18H,10-11,16-17H2,1-3H3,(H,30,35)(H,31,34)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	49	n/a	n/a	n/a	n/a	7.4	n/a
Allergan, Inc. US Patent					Assay Description Biochemical KDR kinase assays were performed in 96 well microliter plates that were coated overnight with 75 .mu.g/well of poly-Glu-Tyr (4:1) in 10 m...				US Patent US8889870 (2014) BindingDB Entry DOI: 10.7270/Q25B0158
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM139626 (US8889870, 174 | US9388176, 174 | US9820989, 174) Show SMILES COC(=O)CNC(=O)c1cncc2CN(CCc12)c1cccc(c1)C(=O)Nc1cccc(c1)C(C)C Show InChI InChI=1S/C28H30N4O4/c1-18(2)19-6-4-8-22(12-19)31-27(34)20-7-5-9-23(13-20)32-11-10-24-21(17-32)14-29-15-25(24)28(35)30-16-26(33)36-3/h4-9,12-15,18H,10-11,16-17H2,1-3H3,(H,30,35)(H,31,34)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	49	n/a	n/a	n/a	n/a	7.4	30
ALLERGAN, INC. US Patent					Assay Description Biochemical KDR kinase assays were performed in 96 well microliter plates that were coated overnight with 75 μg/well of poly-Glu-Tyr (4:1) in 10 m...				US Patent US9388176 (2016) BindingDB Entry DOI: 10.7270/Q2TQ60DZ
					More data for this Ligand-Target Pair