null
SMILES: Cc1nn(C2CCCCC2)c2sc(cc12)C(=O)N[C@H]1CC[C@@H](CC1)N1CCC(O)CC1
InChI Key: InChIKey=MYJKENZQYMVSSC-IYARVYRRSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Phosphodiesterase (Mus musculus (Mouse)) | BDBM140093 (US8901315, 176) | PDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 1.70E+3 | n/a | n/a | n/a | n/a | 6.5 | 4 |
Daiichi Sankyo Company, Limited US Patent | Assay Description The PDE 4 (phosphodiesterase IV) inhibiting effect of the compounds of the present invention was performed by the following method, which was modifie... | US Patent US8901315 (2014) BindingDB Entry DOI: 10.7270/Q2GM860P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A (Homo sapiens (Human)) | BDBM140093 (US8901315, 176) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 20 | n/a | n/a | n/a | n/a | 7.5 | 4 |
Daiichi Sankyo Company, Limited US Patent | Assay Description The PDE 7 (phosphodiesterase VII) inhibiting effect of the compounds of the present invention was performed by the following method, which was modifi... | US Patent US8901315 (2014) BindingDB Entry DOI: 10.7270/Q2GM860P | |||||||||||
More data for this Ligand-Target Pair |