BDBM140105 US8901315, 200

SMILES: CN(C)CCc1ccc(NC(=O)c2cc3c(C)nn(C4CCCCC4)c3s2)cc1

InChI Key: InChIKey=YWNDYELINWISEL-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 140105   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphodiesterase 4 (PDE4) (Mus musculus (Mouse))	BDBM140105 (US8901315, 200) Show SMILES CN(C)CCc1ccc(NC(=O)c2cc3c(C)nn(C4CCCCC4)c3s2)cc1 Show InChI InChI=1S/C23H30N4OS/c1-16-20-15-21(29-23(20)27(25-16)19-7-5-4-6-8-19)22(28)24-18-11-9-17(10-12-18)13-14-26(2)3/h9-12,15,19H,4-8,13-14H2,1-3H3,(H,24,28)	PDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.90E+3	n/a	n/a	n/a	n/a	6.5	4
Daiichi Sankyo Company, Limited US Patent					Assay Description The PDE 4 (phosphodiesterase IV) inhibiting effect of the compounds of the present invention was performed by the following method, which was modifie...				US Patent US8901315 (2014) BindingDB Entry DOI: 10.7270/Q2GM860P
					More data for this Ligand-Target Pair
Phosphodiesterase 7 (Homo sapiens (Human))	BDBM140105 (US8901315, 200) Show SMILES CN(C)CCc1ccc(NC(=O)c2cc3c(C)nn(C4CCCCC4)c3s2)cc1 Show InChI InChI=1S/C23H30N4OS/c1-16-20-15-21(29-23(20)27(25-16)19-7-5-4-6-8-19)22(28)24-18-11-9-17(10-12-18)13-14-26(2)3/h9-12,15,19H,4-8,13-14H2,1-3H3,(H,24,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	16	n/a	n/a	n/a	n/a	7.5	4
Daiichi Sankyo Company, Limited US Patent					Assay Description The PDE 7 (phosphodiesterase VII) inhibiting effect of the compounds of the present invention was performed by the following method, which was modifi...				US Patent US8901315 (2014) BindingDB Entry DOI: 10.7270/Q2GM860P
					More data for this Ligand-Target Pair