null

SMILES: Cc1nn(C2CCOCC2)c2sc(cc12)C(=O)Nc1ccc(nc1)N1CCNC1=O

InChI Key: InChIKey=CWXBOHWOZKONRP-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 140132   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphodiesterase (Mus musculus (Mouse))	BDBM140132 (US8901315, 261) Show SMILES Cc1nn(C2CCOCC2)c2sc(cc12)C(=O)Nc1ccc(nc1)N1CCNC1=O Show InChI InChI=1S/C20H22N6O3S/c1-12-15-10-16(30-19(15)26(24-12)14-4-8-29-9-5-14)18(27)23-13-2-3-17(22-11-13)25-7-6-21-20(25)28/h2-3,10-11,14H,4-9H2,1H3,(H,21,28)(H,23,27)	PDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.90E+3	n/a	n/a	n/a	n/a	6.5	4
Daiichi Sankyo Company, Limited US Patent					Assay Description The PDE 4 (phosphodiesterase IV) inhibiting effect of the compounds of the present invention was performed by the following method, which was modifie...				US Patent US8901315 (2014) BindingDB Entry DOI: 10.7270/Q2GM860P
					More data for this Ligand-Target Pair
High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A (Homo sapiens (Human))	BDBM140132 (US8901315, 261) Show SMILES Cc1nn(C2CCOCC2)c2sc(cc12)C(=O)Nc1ccc(nc1)N1CCNC1=O Show InChI InChI=1S/C20H22N6O3S/c1-12-15-10-16(30-19(15)26(24-12)14-4-8-29-9-5-14)18(27)23-13-2-3-17(22-11-13)25-7-6-21-20(25)28/h2-3,10-11,14H,4-9H2,1H3,(H,21,28)(H,23,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	28	n/a	n/a	n/a	n/a	7.5	4
Daiichi Sankyo Company, Limited US Patent					Assay Description The PDE 7 (phosphodiesterase VII) inhibiting effect of the compounds of the present invention was performed by the following method, which was modifi...				US Patent US8901315 (2014) BindingDB Entry DOI: 10.7270/Q2GM860P
					More data for this Ligand-Target Pair