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SMILES: C[C@@H](Oc1cc(cc2ncccc12)-c1ccccc1)[C@H]1CNC(=O)C1

InChI Key: InChIKey=GEDSNNBMRVNBEQ-RHSMWYFYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 140275   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase SYK (Homo sapiens (Human))	BDBM140275 (US8912173, 1) Show SMILES C[C@@H](Oc1cc(cc2ncccc12)-c1ccccc1)[C@H]1CNC(=O)C1 |r| Show InChI InChI=1S/C21H20N2O2/c1-14(17-12-21(24)23-13-17)25-20-11-16(15-6-3-2-4-7-15)10-19-18(20)8-5-9-22-19/h2-11,14,17H,12-13H2,1H3,(H,23,24)/t14-,17-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.400	n/a	n/a	n/a	n/a	7.5	-80
Boehringer Ingelheim International GmbH US Patent					Assay Description Recombinant human Syk (amino acids 342-635) was expressed as a fusion protein with an N-terminal GST tag, affinity-purified and deep-frozen at a conc...				US Patent US8912173 (2014) BindingDB Entry DOI: 10.7270/Q2TX3D3T
					More data for this Ligand-Target Pair