BDBM140537 US8912221, 10
SMILES: C[C@@H](NC(=O)C1(COC1)NC(=O)c1ccno1)c1ncc(cc1F)-c1cc(Cl)cc(Cl)c1OCC(F)F
InChI Key: InChIKey=QRJFVILHVIPGKL-LLVKDONJSA-N
Data: 1 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Bradykinin B1 receptor (Homo sapiens (Human)) | BDBM140537 (US8912221, 10) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 4.70 | n/a | n/a | n/a | n/a | n/a | n/a | 7.4 | n/a |
Hoffmann-La Roche Inc. US Patent | Assay Description For binding, Bradykinin-1 receptor antagonist compounds were added in various concentrations in 50 mM Tris pH 7.4, 5 mM MgCl2 together with 6 nM Kall... | US Patent US8912221 (2014) BindingDB Entry DOI: 10.7270/Q2668BWC | |||||||||||
More data for this Ligand-Target Pair |