BDBM140540 US8912221, 13

SMILES: COC(=O)c1c(Cl)cccc1-c1ccc([C@@H](C)NC(=O)C2(COC2)NC(=O)c2cc(C)no2)c(F)c1

InChI Key: InChIKey=FNUJSJPEYKYQDN-CQSZACIVSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 140540   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Bradykinin B1 receptor (Homo sapiens (Human))	BDBM140540 (US8912221, 13) Show SMILES COC(=O)c1c(Cl)cccc1-c1ccc([C@@H](C)NC(=O)C2(COC2)NC(=O)c2cc(C)no2)c(F)c1 |r| Show InChI InChI=1S/C25H23ClFN3O6/c1-13-9-20(36-30-13)22(31)29-25(11-35-12-25)24(33)28-14(2)16-8-7-15(10-19(16)27)17-5-4-6-18(26)21(17)23(32)34-3/h4-10,14H,11-12H2,1-3H3,(H,28,33)(H,29,31)/t14-/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	1	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description For binding, Bradykinin-1 receptor antagonist compounds were added in various concentrations in 50 mM Tris pH 7.4, 5 mM MgCl2 together with 6 nM Kall...				US Patent US8912221 (2014) BindingDB Entry DOI: 10.7270/Q2668BWC
					More data for this Ligand-Target Pair