BDBM140551 US8912221, 24

SMILES: C[C@@H](NC(=O)C1(COC1)NC(=O)c1cc(C)no1)c1ccc(cc1F)-c1cc(Cl)cc(F)c1-c1noc(C)n1

InChI Key: InChIKey=JEISKSYXIZFGBQ-CYBMUJFWSA-N

Data: 1 KI

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Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 140551   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
B1 bradykinin receptor (Homo sapiens (Human))	BDBM140551 (US8912221, 24) Show SMILES C[C@@H](NC(=O)C1(COC1)NC(=O)c1cc(C)no1)c1ccc(cc1F)-c1cc(Cl)cc(F)c1-c1noc(C)n1 |r| Show InChI InChI=1S/C26H22ClF2N5O5/c1-12-6-21(39-33-12)24(35)32-26(10-37-11-26)25(36)30-13(2)17-5-4-15(7-19(17)28)18-8-16(27)9-20(29)22(18)23-31-14(3)38-34-23/h4-9,13H,10-11H2,1-3H3,(H,30,36)(H,32,35)/t13-/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	1.20	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description For binding, Bradykinin-1 receptor antagonist compounds were added in various concentrations in 50 mM Tris pH 7.4, 5 mM MgCl2 together with 6 nM Kall...				US Patent US8912221 (2014) BindingDB Entry DOI: 10.7270/Q2668BWC
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