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SMILES: C[C@@H](NC(=O)C1(COC1)NC(=O)c1ccno1)c1ccc(cc1F)-c1cc(Cl)cc(Cl)c1OCC(F)F

InChI Key: InChIKey=TVIHSGNVGMFCOO-GFCCVEGCSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 140559   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
B1 bradykinin receptor


(Homo sapiens (Human))		BDBM140559
PNG
(US8912221, 32)
Show SMILES C[C@@H](NC(=O)C1(COC1)NC(=O)c1ccno1)c1ccc(cc1F)-c1cc(Cl)cc(Cl)c1OCC(F)F |r|
Show InChI InChI=1S/C24H20Cl2F3N3O5/c1-12(31-23(34)24(10-35-11-24)32-22(33)19-4-5-30-37-19)15-3-2-13(6-18(15)27)16-7-14(25)8-17(26)21(16)36-9-20(28)29/h2-8,12,20H,9-11H2,1H3,(H,31,34)(H,32,33)/t12-/m1/s1
PDB

KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars
US Patent
 2.30n/an/an/an/an/an/a7.4n/a



Hoffmann-La Roche Inc.

US Patent


Assay Description
For binding, Bradykinin-1 receptor antagonist compounds were added in various concentrations in 50 mM Tris pH 7.4, 5 mM MgCl2 together with 6 nM Kall...

US Patent US8912221 (2014)


BindingDB Entry DOI: 10.7270/Q2668BWC
More data for this
Ligand-Target Pair