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SMILES: C[C@@H](NC(=O)C1(COC1)NC(=O)c1nnc(C)o1)c1ccc(cc1F)-c1cc(Cl)cc(Cl)c1OCC(F)F

InChI Key: InChIKey=QUODQZASWJEYAM-LLVKDONJSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 140565   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
B1 bradykinin receptor


(Homo sapiens (Human))		BDBM140565
PNG
(US8912221, 38)
Show SMILES C[C@@H](NC(=O)C1(COC1)NC(=O)c1nnc(C)o1)c1ccc(cc1F)-c1cc(Cl)cc(Cl)c1OCC(F)F |r|
Show InChI InChI=1S/C24H21Cl2F3N4O5/c1-11(30-23(35)24(9-36-10-24)31-21(34)22-33-32-12(2)38-22)15-4-3-13(5-18(15)27)16-6-14(25)7-17(26)20(16)37-8-19(28)29/h3-7,11,19H,8-10H2,1-2H3,(H,30,35)(H,31,34)/t11-/m1/s1
PDB

KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
 4.30n/an/an/an/an/an/a7.4n/a



Hoffmann-La Roche Inc.

US Patent


Assay Description
For binding, Bradykinin-1 receptor antagonist compounds were added in various concentrations in 50 mM Tris pH 7.4, 5 mM MgCl2 together with 6 nM Kall...

US Patent US8912221 (2014)


BindingDB Entry DOI: 10.7270/Q2668BWC
More data for this
Ligand-Target Pair