BDBM140936 US8916553, 147
SMILES: COc1ccc(cc1)S(=O)(=O)Nc1ccc(c(OC)c1)-c1cncc2ccccc12
InChI Key: InChIKey=ZLLXYXKUIHRXPR-UHFFFAOYSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Cytochrome P450 17A1 (Homo sapiens (Human)) | BDBM140936 (US8916553, 147) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 2.70 | n/a | n/a | n/a | n/a | 7.2 | 4 |
Bristol-Myers Squibb Company US Patent | Assay Description The assays were performed in U-bottom 384-well optiplates. The final assay volume was 15 ul prepared from 7.5 ul additions of microsomes (prepared as... | US Patent US8916553 (2014) BindingDB Entry DOI: 10.7270/Q2XP73N9 | |||||||||||
More data for this Ligand-Target Pair |