null

SMILES: CCCC(=O)Nc1cccc(c1)-c1nc(Nc2ccc3[nH]ncc3c2)c2cc(OCCN3CCCC3=O)ccc2n1

InChI Key: InChIKey=WIWLMHOAKGHQBF-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 141000   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Rho-associated protein kinase 2 (Homo sapiens (Human))	BDBM141000 (US10570123, Example 204 | US8916576, 204) Show SMILES CCCC(=O)Nc1cccc(c1)-c1nc(Nc2ccc3[nH]ncc3c2)c2cc(OCCN3CCCC3=O)ccc2n1 Show InChI InChI=1S/C31H31N7O3/c1-2-5-28(39)33-22-7-3-6-20(16-22)30-35-27-12-10-24(41-15-14-38-13-4-8-29(38)40)18-25(27)31(36-30)34-23-9-11-26-21(17-23)19-32-37-26/h3,6-7,9-12,16-19H,2,4-5,8,13-15H2,1H3,(H,32,37)(H,33,39)(H,34,35,36)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	150	n/a	n/a	n/a	n/a	n/a	n/a
Surface Logix, Inc. US Patent					Assay Description ROCK-II inhibitory activity can be measured using the ROCK-II Assay Kit (Molecular Devices, inc.; Sunnyvale, Calif.).				US Patent US8916576 (2014) BindingDB Entry DOI: 10.7270/Q2P55M6K
					More data for this Ligand-Target Pair
Rho-associated protein kinase 2 (Homo sapiens (Human))	BDBM141000 (US10570123, Example 204 | US8916576, 204) Show SMILES CCCC(=O)Nc1cccc(c1)-c1nc(Nc2ccc3[nH]ncc3c2)c2cc(OCCN3CCCC3=O)ccc2n1 Show InChI InChI=1S/C31H31N7O3/c1-2-5-28(39)33-22-7-3-6-20(16-22)30-35-27-12-10-24(41-15-14-38-13-4-8-29(38)40)18-25(27)31(36-30)34-23-9-11-26-21(17-23)19-32-37-26/h3,6-7,9-12,16-19H,2,4-5,8,13-15H2,1H3,(H,32,37)(H,33,39)(H,34,35,36)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	110	n/a	n/a	n/a	n/a	n/a	n/a
Surface Logix, Inc. US Patent					Assay Description ROCK-II inhibitory activity can be measured using the ROCK-II Assay Kit (Molecular Devices, inc.; Sunnyvale, Calif.).				US Patent US8916576 (2014) BindingDB Entry DOI: 10.7270/Q2P55M6K
					More data for this Ligand-Target Pair
Rho-associated protein kinase 2 (Homo sapiens (Human))	BDBM141000 (US10570123, Example 204 | US8916576, 204) Show SMILES CCCC(=O)Nc1cccc(c1)-c1nc(Nc2ccc3[nH]ncc3c2)c2cc(OCCN3CCCC3=O)ccc2n1 Show InChI InChI=1S/C31H31N7O3/c1-2-5-28(39)33-22-7-3-6-20(16-22)30-35-27-12-10-24(41-15-14-38-13-4-8-29(38)40)18-25(27)31(36-30)34-23-9-11-26-21(17-23)19-32-37-26/h3,6-7,9-12,16-19H,2,4-5,8,13-15H2,1H3,(H,32,37)(H,33,39)(H,34,35,36)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	67	n/a	n/a	n/a	n/a	n/a	n/a
SURFACE LOGIX, LLC US Patent					Assay Description ROCK-II inhibitory activity can be measured using the ROCK-II Assay Kit (Molecular Devices, inc.; Sunnyvale, Calif.).				US Patent US10570123 (2020) BindingDB Entry DOI: 10.7270/Q2542R1V
					More data for this Ligand-Target Pair
Rho-associated protein kinase 2 (Homo sapiens (Human))	BDBM141000 (US10570123, Example 204 | US8916576, 204) Show SMILES CCCC(=O)Nc1cccc(c1)-c1nc(Nc2ccc3[nH]ncc3c2)c2cc(OCCN3CCCC3=O)ccc2n1 Show InChI InChI=1S/C31H31N7O3/c1-2-5-28(39)33-22-7-3-6-20(16-22)30-35-27-12-10-24(41-15-14-38-13-4-8-29(38)40)18-25(27)31(36-30)34-23-9-11-26-21(17-23)19-32-37-26/h3,6-7,9-12,16-19H,2,4-5,8,13-15H2,1H3,(H,32,37)(H,33,39)(H,34,35,36)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	151	n/a	n/a	n/a	n/a	n/a	n/a
SURFACE LOGIX, LLC US Patent					Assay Description ROCK-II inhibitory activity can be measured using the ROCK-II Assay Kit (Molecular Devices, inc.; Sunnyvale, Calif.).				US Patent US10570123 (2020) BindingDB Entry DOI: 10.7270/Q2542R1V
					More data for this Ligand-Target Pair
Rho-associated protein kinase 2 (Homo sapiens (Human))	BDBM141000 (US10570123, Example 204 | US8916576, 204) Show SMILES CCCC(=O)Nc1cccc(c1)-c1nc(Nc2ccc3[nH]ncc3c2)c2cc(OCCN3CCCC3=O)ccc2n1 Show InChI InChI=1S/C31H31N7O3/c1-2-5-28(39)33-22-7-3-6-20(16-22)30-35-27-12-10-24(41-15-14-38-13-4-8-29(38)40)18-25(27)31(36-30)34-23-9-11-26-21(17-23)19-32-37-26/h3,6-7,9-12,16-19H,2,4-5,8,13-15H2,1H3,(H,32,37)(H,33,39)(H,34,35,36)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	67	n/a	n/a	n/a	n/a	n/a	n/a
SURFACE LOGIX, LLC US Patent					Assay Description ROCK-II inhibitory activity can be measured using the ROCK-II Assay Kit (Molecular Devices, inc.; Sunnyvale, Calif.).				US Patent US10570123 (2020) BindingDB Entry DOI: 10.7270/Q2542R1V
					More data for this Ligand-Target Pair
Rho-associated protein kinase 2 (Homo sapiens (Human))	BDBM141000 (US10570123, Example 204 | US8916576, 204) Show SMILES CCCC(=O)Nc1cccc(c1)-c1nc(Nc2ccc3[nH]ncc3c2)c2cc(OCCN3CCCC3=O)ccc2n1 Show InChI InChI=1S/C31H31N7O3/c1-2-5-28(39)33-22-7-3-6-20(16-22)30-35-27-12-10-24(41-15-14-38-13-4-8-29(38)40)18-25(27)31(36-30)34-23-9-11-26-21(17-23)19-32-37-26/h3,6-7,9-12,16-19H,2,4-5,8,13-15H2,1H3,(H,32,37)(H,33,39)(H,34,35,36)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	67	n/a	n/a	n/a	n/a	n/a	n/a
Surface Logix, Inc. US Patent					Assay Description ROCK-II inhibitory activity can be measured using the ROCK-II Assay Kit (Molecular Devices, inc.; Sunnyvale, Calif.).				US Patent US8916576 (2014) BindingDB Entry DOI: 10.7270/Q2P55M6K
					More data for this Ligand-Target Pair