BDBM141002 US10570123, Example 206::US8916576, 206
SMILES: CCCC(=O)Nc1cccc(c1)-c1nc(Nc2ccc3[nH]ncc3c2)c2cc(OCCN3CCCC3=O)c(OC)cc2n1
InChI Key: InChIKey=JLDIMPXARFWITP-UHFFFAOYSA-N
Data: 4 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Rho-associated protein kinase 2 (Homo sapiens (Human)) | BDBM141002 (US10570123, Example 206 | US8916576, 206) | PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 48 | n/a | n/a | n/a | n/a | n/a | n/a |
Surface Logix, Inc. US Patent | Assay Description ROCK-II inhibitory activity can be measured using the ROCK-II Assay Kit (Molecular Devices, inc.; Sunnyvale, Calif.). | US Patent US8916576 (2014) BindingDB Entry DOI: 10.7270/Q2P55M6K | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Rho-associated protein kinase 2 (Homo sapiens (Human)) | BDBM141002 (US10570123, Example 206 | US8916576, 206) | PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 64 | n/a | n/a | n/a | n/a | n/a | n/a |
SURFACE LOGIX, LLC US Patent | Assay Description ROCK-II inhibitory activity can be measured using the ROCK-II Assay Kit (Molecular Devices, inc.; Sunnyvale, Calif.). | US Patent US10570123 (2020) BindingDB Entry DOI: 10.7270/Q2542R1V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Rho-associated protein kinase 2 (Homo sapiens (Human)) | BDBM141002 (US10570123, Example 206 | US8916576, 206) | PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 48 | n/a | n/a | n/a | n/a | n/a | n/a |
SURFACE LOGIX, LLC US Patent | Assay Description ROCK-II inhibitory activity can be measured using the ROCK-II Assay Kit (Molecular Devices, inc.; Sunnyvale, Calif.). | US Patent US10570123 (2020) BindingDB Entry DOI: 10.7270/Q2542R1V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Rho-associated protein kinase 2 (Homo sapiens (Human)) | BDBM141002 (US10570123, Example 206 | US8916576, 206) | PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 64 | n/a | n/a | n/a | n/a | n/a | n/a |
Surface Logix, Inc. US Patent | Assay Description ROCK-II inhibitory activity can be measured using the ROCK-II Assay Kit (Molecular Devices, inc.; Sunnyvale, Calif.). | US Patent US8916576 (2014) BindingDB Entry DOI: 10.7270/Q2P55M6K | |||||||||||
More data for this Ligand-Target Pair |