BDBM141396 US10668051, Compound Example 7::US8921364, 7

SMILES: Cc1ccccc1C(=O)Nc1ccc(cc1)-n1nc(cc1C1CC1)C1CC1

InChI Key: InChIKey=XKCPTMMOWPCFIC-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 141396   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Calcium release-activated calcium channel (Homo sapiens (Human))	BDBM141396 (US10668051, Compound Example 7 | US8921364, 7) Show SMILES Cc1ccccc1C(=O)Nc1ccc(cc1)-n1nc(cc1C1CC1)C1CC1 Show InChI InChI=1S/C23H23N3O/c1-15-4-2-3-5-20(15)23(27)24-18-10-12-19(13-11-18)26-22(17-8-9-17)14-21(25-26)16-6-7-16/h2-5,10-14,16-17H,6-9H2,1H3,(H,24,27)	KEGG UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	36.4	n/a	n/a	n/a	n/a	n/a	n/a
RHIZEN PHARMACEUTICALS SA US Patent					Assay Description Inhibition of CRAC channels was determined following thapsigargin (Sigma, Cat #T9033) induced endoplasmic calcium release in Jurkat cells, (see Yasur...				US Patent US10668051 (2020)
					More data for this Ligand-Target Pair
Calcium release-activated calcium (CRAC) (Homo sapiens (Human))	BDBM141396 (US10668051, Compound Example 7 | US8921364, 7) Show SMILES Cc1ccccc1C(=O)Nc1ccc(cc1)-n1nc(cc1C1CC1)C1CC1 Show InChI InChI=1S/C23H23N3O/c1-15-4-2-3-5-20(15)23(27)24-18-10-12-19(13-11-18)26-22(17-8-9-17)14-21(25-26)16-6-7-16/h2-5,10-14,16-17H,6-9H2,1H3,(H,24,27)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	36.4	n/a	n/a	n/a	n/a	n/a	37
Rhizen Pharmaceuticals SA US Patent					Assay Description Inhibition of CRAC channels was determined following thapsigargin (Sigma, Cat # T9033) induced endoplasmic calcium release in Jurkat cells. (see Yasu...				US Patent US8921364 (2014) BindingDB Entry DOI: 10.7270/Q2N58K3N
					More data for this Ligand-Target Pair