BDBM141976 US8927534, 23
SMILES: Cc1cc(C)c(C(=O)NC(Cc2ccc(cc2)N2CCC(CC2)c2ccc3CCCNc3n2)C(O)=O)c(C)c1
InChI Key: InChIKey=RWENQEHCTSXFGI-UHFFFAOYSA-N
Data: 2 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Integrin alpha-IIb (Homo sapiens (Human)) | BDBM141976 (US8927534, 23) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a | 9.6 | 4 |
Shire Orphan Therapies GmbH US Patent | Assay Description Fibrinogen was diluted with coating buffer (15 mM Na2CO3, 35 mM NaHCO3, pH 9.6) and coated with 100 uL/well to Nunc-Immuno maxisorp plates over night... | US Patent US8927534 (2015) BindingDB Entry DOI: 10.7270/Q2TQ607Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin alpha-5 (Homo sapiens (Human)) | BDBM141976 (US8927534, 23) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | 9.6 | 4 |
Shire Orphan Therapies GmbH US Patent | Assay Description Fibronectin was diluted with coating buffer (15 mM Na2CO3, 35 mM NaHCO3, pH 9.6) and coated with 100 uL/well to Nunc-Immuno maxisorp plates (Nalge Nu... | US Patent US8927534 (2015) BindingDB Entry DOI: 10.7270/Q2TQ607Q | |||||||||||
More data for this Ligand-Target Pair |