BDBM141978 US8927534, 29
SMILES: CC1(CCCCC1)C(=O)NC(CC1CCN(CC1)C(=O)CCc1ccc2CCCNc2n1)C(O)=O
InChI Key: InChIKey=BQIRKRXYFAKFJD-UHFFFAOYSA-N
Data: 2 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Integrin alpha-IIb (Homo sapiens (Human)) | BDBM141978 (US8927534, 29) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a | 9.6 | 4 |
Shire Orphan Therapies GmbH US Patent | Assay Description Fibrinogen was diluted with coating buffer (15 mM Na2CO3, 35 mM NaHCO3, pH 9.6) and coated with 100 uL/well to Nunc-Immuno maxisorp plates over night... | US Patent US8927534 (2015) BindingDB Entry DOI: 10.7270/Q2TQ607Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin alpha-5 (Homo sapiens (Human)) | BDBM141978 (US8927534, 29) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | 9.6 | 4 |
Shire Orphan Therapies GmbH US Patent | Assay Description Fibronectin was diluted with coating buffer (15 mM Na2CO3, 35 mM NaHCO3, pH 9.6) and coated with 100 uL/well to Nunc-Immuno maxisorp plates (Nalge Nu... | US Patent US8927534 (2015) BindingDB Entry DOI: 10.7270/Q2TQ607Q | |||||||||||
More data for this Ligand-Target Pair |