BDBM142042 US8927577, 23

SMILES: CC1(C)CC(C1)C(Nc1cnc2ccc(F)cc2c1)c1ccc(cc1)C(=O)NCCC(O)=O

InChI Key: InChIKey=MNPUWRWCAJUYKB-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 142042   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glucagon (Homo sapiens (Human))	BDBM142042 (US8927577, 23) Show SMILES CC1(C)CC(C1)C(Nc1cnc2ccc(F)cc2c1)c1ccc(cc1)C(=O)NCCC(O)=O Show InChI InChI=1S/C26H28FN3O3/c1-26(2)13-19(14-26)24(30-21-12-18-11-20(27)7-8-22(18)29-15-21)16-3-5-17(6-4-16)25(33)28-10-9-23(31)32/h3-8,11-12,15,19,24,30H,9-10,13-14H2,1-2H3,(H,28,33)(H,31,32)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	50	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
Pfizer Inc. US Patent					Assay Description The Glucagon SPA assay is used to determine the ability of test compounds to block the binding of glucagon-cex to the glucagon receptor. Test compoun...				US Patent US8927577 (2015) BindingDB Entry DOI: 10.7270/Q29S1PRV
					More data for this Ligand-Target Pair